The Islands of the Firth of Clyde are the fifth of the major Scottish island groups after the Inner and Outer Hebrides, Orkney and Shetland. The islands are situated in the Firth of Clyde between Ayrshire and Argyll. There are about forty islands and skerries, of which only six are inhabited. The largest and most populous are Arran and Bute, and Great Cumbrae, Holy Isle and Inchmarnock are also served by dedicated ferry routes.

 The Isle of Arran is the largest island in the Firth of Clyde, with an area of 430 km² (167 square miles). It is in the unitary council area of North Ayrshire. In the 2001 census it had a resident population of 5,058. Arran is the seventh largest Scottish island and the ninth largest island surrounding Great Britain (excluding Ireland). Arran is commonly associated with the Hebrides, with which it shares many cultural and physical similarities, but in actual fact, the Hebrides start off the west coast of Kintyre.

The Burnt Islands is the collective title for three small islands that lie in the Kyles of Bute off the west coast of the Scottish mainland. Individually the Islands are known by their Gaelic names. From the largest to the smallest they are Eilean Mòr (Large Island), Eilean Fraoich (Heather Island) and Eilean Buidhe (Yellow Island). Oddly only the smallest of these tiny islets, Eilean Buidhe, shows any sign of ever having been permanently inhabited having the remains of a vitrified fort on it. Eilean Mòr, huge in comparison supports only a little stunted woodland at its northern end.

The Holy Isle, Firth of Clyde is one of a number of islands in the United Kingdom which go under the name "Holy Island". It is located in the Firth of Clyde off the west coast of central Scotland, inside Lamlash Bay on the larger island of Arran. Holy Isle seen from Arran The island is around 3 kilometre (2 miles) long and around 1 km (around half a mile) wide. Its highest point is the hill Mullach Mòr. The island has a long history as a sacred site, with a spring said to have healing properties, the hermit cave of 6th Century monk Saint Molaise, and evidence of a 13th Century monastery.

Great Cumbrae also known as Cumbrae or the Isle of Cumbrae) is the larger of the two islands known as The Cumbraes in the lower Firth of Clyde. Home to the National Watersports Centre, the Cathedral of the Isles and the University Marine Biological Station, Millport, the holiday island has an 18-hole golf course which sweeps almost to the summit, and a round-island road much favoured for family cycle runs. Population is about 1500.

The Isle of Bute  is one of the islands of the lower Firth of Clyde in Scotland. Formerly part of the county of Buteshire, it now constitutes part of the council area of Argyll and Bute. In the 2001 census (conducted in April 2001) it had a resident population of 7,228. However, many flats are in fact summer holiday homes, and in winter there are probably fewer than 5,000 people on the island.